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- $Unique_ID{BRK00316}
- $Pretitle{}
- $Title{Colitis Caused by Antibiotics}
- $Subject{colitis antibiotic diarrhea bacterial Infections infection parasite
- Parasites bacteria bacterium digestive antibiotics intestines resistant
- friendly germs Clostridium difficile fever antibiotic associated dehydration
- hypotension low blood pressure perforation colon colonoscopy colonoscopic
- stool culture cultures infection toxins toxin colonoscopies}
- $Volume{A-12}
- $Log{
- Colonoscopy*0002800.tid
- Discussion of Colonoscopy*0002801.scf
- Colonoscopic View of Colon Conditions*0002803.scf}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
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-
- Colitis Caused by Antibiotics
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-
- QUESTION: After a recent chest infection, I developed a terrible bout of
- diarrhea. This came on with severe stomach cramps and weakness. I took some
- medicine we had at home, but to no avail. When I finally visited my doctor,
- he performed a complete examination with a scope, and informed me that I had
- colitis that was caused by antibiotics. Despite my request, the doctor gave
- me no medications. I am wondering about both the diagnosis and the treatment.
- Will you please comment?
-
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-
- ANSWER: You may be aware of the fact that many types of bacteria normally
- live in our digestive system without causing us any ill effects. However,
- when antibiotics are given to combat infections in any portion of our body,
- these potent medications kill the normal bacteria in the intestines as well
- and allow certain resistant bacteria types to take over the territory usually
- occupied by the "friendly" germs. The most frequently recognized, Clostridium
- difficile, is a gram-positive rod that produces a poison that can damage the
- cells that line the colon. When this occurs, all the symptoms which you
- experienced may be provoked; diarrhea, abdominal pain, and fever. In some
- cases the disease, known as "antibiotic associated colitis," may be so severe
- that dehydration, hypotension (low blood pressure) and even perforation of the
- colon may occur. The diagnosis is based upon the findings of a colonoscopy
- (examination of the colon with a telescope-like instrument) as well as the
- results of a stool culture which finds the presence of Clostridium difficile,
- and the history of recent use of antibiotics. Taking medications which reduce
- the normal movement of the bowels (peristalsis), and which can help with
- ordinary diarrhea, is a no-no in this case as it may prolong the time that the
- bacteria and toxins remain in contact with the tissue of the colon. Treatment
- varies with the severity of the disease and the findings of the colonoscopic
- exam, but always requires stopping the antibiotic. Once the antibiotic has
- been discontinued, the colitis will generally subside by itself in 10 to 12
- days, without any additional medication or treatment. Although the presence
- of the bacterial toxin may remain for several months, no further treatment is
- necessary if you remain without symptoms.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
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-